Tracking the pipeline: immunoinformatics and the COVID-19 vaccine design

Abstract With the onset of COVID-19 pandemic, amount data on genomic and proteomic sequences severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stored in various databases has exponentially grown. A large volume these led to production equally immense sets immunological data, which require rigorous computational approaches sort through make sense of. Immunoinformatics emerged recent decades as a field capable offering this approach by bridging experimental theoretical immunology with state-of-the-art tools. Here, we discuss how immunoinformatics can assist development high-performance vaccines drug discovery needed curb spread SARS-CoV-2. provide set tools extract meaningful connections from patient be implemented design effective vaccines. mind, represent pipeline identify role treatment vaccine development. In process, number free protein sequences, structures mutations are introduced, along docking web servers for assessing interaction between antibodies SARS-CoV-2 spike segments most commonly considered antigens design.